Climbing fiber-mediated spillover transmission to interneurons is regulated by EAAT4.
Malhotra S, Banumurthy G, Pennock R, Vaden JH, Sugihara I, Overstreet-Wadiche L & Wadiche JI (2021). J. Neurosci., in press.
RGS6 mediates effects of voluntary running on adult hippocampal neurogenesis.
Gao Y, Shen M, Gonzalez JC, Dong Q, Kannan S, Hoang JT, Eisinger BE, Pandey J, Javadi S, Chang Q, Wang D, Overstreet-Wadiche L & Zhao X (2020). Cell Reports, 32:107997.
Parvalbumin interneurons provide spillover to newborn and mature dentate granule cells.
Vaden RJ, Gonzalez JC, Tsai MC, Niver, AJ, Fusilier AR, Griffith CM, Kramer RH, Wadiche JI & Overstreet-Wadiche L (2020). eLife, 2019; 9:e54125.
A Role for PGC-1α in Transcription and Excitability of Neocortical and Hippocampal Excitatory Neurons.
McMeekin LJ, Bartley AF, Bohannon AS, Adlaf EW, van Groen T, Boas SM, Fox SN, Detloff PJ, Crossman DK, Overstreet-Wadiche LS, Hablitz JJ, Dobrunz LE, Cowell RM (2020). Neuroscience, 435:73.
Multifaceted circuit functions of adult-born neurons.
Dieni CV, Gonzalez JC & Overstreet-Wadiche L (2019). F1000Research, 8 (F1000 Faculty Rev):1998.
The readily-releasable pool dynamically regulates multivesicular release.
Vaden JH, Banumurthy G, Gusarevich ES, Overstreet-Wadiche L & Wadiche JI (2019). eLife, 2019; 8:e47434.
NeuroD2 controls inhibitory circuit formation in the molecular layer of the cerebellum.
Pieper A, Rudolph S, Wieser GL, Götze T, Mießner H, Yonemasu T, Yan K, Tzvetanova I, Castillo BD, Bode U, Bormuth I, Wadiche JI, Schwab MH & Goebbels S (2019). Sci.Rep. 9:1448.
Constitutive and synaptic activation of GIRK channels differentiates mature and newborn dentate granule cells.
Gonzalez JC, Epps SA, Markwardt SJ, Wadiche JI & Overstreet-Wadiche L (2018). J Neurosci. 38:6513-6526.
α-Synuclein fibril-induced paradoxical structural and functional defects in hippocampal neurons.
Froula JM, Henderson BW, Gonzalez JC, Vaden JH, Mclean JW, Wu Y, Banumurthy G, Overstreet-Wadiche L, Herskowitz JH & Volpicelli-Daley LA (2018). Acta Neuropathol. Commun. 6:35.
Non-synaptic signaling from cerebellar climbing fibers modulates Golgi cell activity.
Nietz AK, Vaden JH, Coddington LT, Overstreet-Wadiche L & Wadiche JI (2017). eLife, 2017;6:e29215.
Klotho regulates postnatal neurogenesis and protects against age-related spatial memory loss.
Laszczyk AM, Fox-Quick S, Vo HT, Nettles D, Pugh PC, Overstreet-Wadiche L & King GD (2017). Neurobiol Aging. 59:41-54.
Adult born neurons modify excitatory synaptic transmission to existing neurons.
Adlaf EW, Vaden RJ, Niver, AJ, Manuel AF, Onyilo VC, Araujo MT, Dieni CV, Vo HT, King GD, Wadiche JI & Overstreet-Wadiche LS (2017). eLife, 2017;6:e19886.
Low excitatory innervation balances high intrinsic excitability of immature dentate neurons.
Dieni CV, Panichi R, Aimone JB, Kuo CT, Wadiche JI & Overstreet-Wadiche L (2016). Nat. Comm., 7:11313.
Porcupine controls hippocampal AMPAR levels, composition, and synaptic transmission.
Erlenhardt N, Yu H, Abiraman K, Yamasaki T, Wadiche JI, Tomita S & Bredt DS (2016). Cell Rep. 14:782-794.
The ubiquitous nature of multivesicular release.
Rudolph S, VonGersdorff H & Wadiche JI (2015). Trends in Neurosciences 38:428-38.
New neurons don't talk back.
Wadiche JI & Overstreet-Wadiche L (2015). Neuron. 7;85:3-5.
Neurogliaform cells in cortical circuits.
Overstreet-Wadiche L & McBain CJ (2015). Nat Rev Neurosci.16:458-68.
Development of glutamatergic innervation during maturation of adult-born neurons.
Dieni CV, Wieckert AJ & Overstreet-Wadiche L (2015). Frontiers in Biology. 10:310-320.
Viral and transgenic reporters and genetic analysis of adult neurogenesis.
Enikolopov G, Overstreet-Wadiche L & Ge S (2015). Cold Spring Harb Perspect Biol. 7:a018804.
Good housekeeping.
Overstreet-Wadiche L, Wadiche JI (2014). Neuron. 81:715-7.
Hilar mossy cells provide the first glutamatergic synapses to adult-born dentate granule cells.
Chancey JH, Poulsen DJ, Wadiche JI & Overstreet-Wadiche L (2014). J Neurosci. 34:2349-54.
The contribution of extrasynaptic signaling to cerebellar information processing.
Coddington LT, Nietz AK & Wadiche JI (2014). Cerebellum 13:513-20.
Distinct determinants of sparse activation during granule cell maturation.
Dieni CV, Nietz AK, Panichi R, Wadiche JI & Overstreet-Wadiche L (2013). J Neurosci., 33:19131-42.
Spillover-mediated feedforward inhibition functionally segregates interneuron activity.
Coddington LT, Rudolph S, Vande Lune P, Overstreet-Wadiche L & Wadiche JI (2013). Neuron, 78:1050-62.
GABA depolarization is required for experience-dependent synapse unsilencing in adult born neurons.
Chancey JH, Adlaf EW, Sapp MC, Pugh PC, Wadiche JI & Overstreet-Wadiche LS (2013). J. Neurosci, 33:6614-22.
Neuronal glutamate transporters regulate glial excitatory transmission.
Tsai MC, Tanaka K, Overstreet-Wadiche L* & Wadiche JI* (2012). J. Neurosci., 32:1528-35.
Dynamic functions of GABA signaling during granule cell maturation.
Dieni CV, Chancey JH & Overstreet-Wadiche LS (2013). Frontiers in Neural Circuits, 6:113.
Desynchronization of multivesicular release enhances Purkinje cell output.
Rudolph S, Overstreet-Wadiche L & Wadiche JI (2011). Neuron, 70:991-1004.
Ivy/Neurogliaform interneurons coordinate activity in the neurogenic niche.
Markwardt SJ, Dieni CV, Wadiche JI & Overstreet-Wadiche L (2011). Nat. Neurosci. 14:1407-09.
Enhanced integration of newborn neurons after neonatal insults.
Pugh PC, Adlaf E, Zhao CS, Markwardt SJ, Gavin C, Wadiche J & Overstreet-Wadiche L (2011). Front Neurosci.,5:45.
Adult hippocampal neurogenesis and plasticity in the infrapyramidal bundle of the mossy fiber projection: I. Co-regulation by activity.
Römer B, Krebs J, Overall RW, Fabel K, Babu H, Overstreet-Wadiche L, Brandt M, Williams RW, Jessberger S, Kempermann G (2011). Frontiers in Neurogenesis, 5:107.
Parvalbumin deficiency and GABAergic dysfunction in mice lacking PGC-1alpha.
Lucas EK, Markwardt SJ, Gupta S, Meador-Woodruff JH, Lin JD, Overstreet-Wadiche L & Cowell RM (2010). J Neurosci. 30:7227-35.
Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis.
Sierra A, Encinas JM, Deudero JJ, Chancey JH, Enikolopov G, Overstreet-Wadiche LS, Tsirka SE & Maletic-Savatic M (2010). Cell Stem Cell 7:483-95.
Adult neurogenesis, mental health, and mental illness: hope or hype?
Eisch AJ, Cameron HA, Encinas JM, Meltzer LA, Ming GL & Overstreet-Wadiche LS (2010). J Neurosci. 28:11785-91.
Input-specific GABAergic signaling to newborn neurons in adult dentate gyrus.
Markwardt SJ, Wadiche JI & Overstreet-Wadiche LS (2009). J. Neurosci., 29:15063-72.
Integration of adult generated neurons during epileptogenesis.
Zhao CS & Overstreet-Wadiche L (2008). Epilepsia 49 Suppl 5:3-12.
GABAergic signalling to adult-generated neurons.
Markwardt S & Overstreet-Wadiche L (2008). J Physiol. 586:3745-9.
Long-distance signaling via presynaptic glutamate transporters.
Wadiche JI & von Gersdorff H (2006). Nat Neurosci., 9, 1352-3.
Seizures accelerate functional integration of adult-generated granule cells.
Overstreet-Wadiche LS, Bromberg DA, Bensen AL & Westbrook GL (2006). J Neurosci. 26:4095-103.
Intrinsic kinetics determines the time course of neuronal synaptic transporter currents.
Wadiche JI, Tzingounis AV & Jahr CE (2006). PNAS, 103:1083-7.
Delayed development of adult-generated granule cells in dentate gyrus.
Overstreet-Wadiche LS, Bensen AL & Westbrook GL (2006). J Neurosci. 26:2326-34.
Functional maturation of adult-generated granule cells.
Overstreet-Wadiche LS & Westbrook GL (2006). Hippocampus, 16:208-15
Patterned expression of Purkinje cell glutamate transporters controls synaptic plasticity.
Wadiche JI & Jahr CE (2005). Nat. Neurosci., 8:1329-34.
GABAergic signaling to newborn neurons in dentate gyrus.
Overstreet Wadiche L, Bromberg DA, Bensen AL & Westbrook GL (2005). J. Neurophys. 94:4528-32.
New neurons in the adult mammalian brain: synaptogenesis and functional integration.
Song H, Kempermann G, Overstreet-Wadiche L, Zhao C, Schinder AF & Bischofberger J (2005). J. Neurosci. 25:10366-8.
Retroinhibition of presynaptic Ca2+ currents by endocannabinoids released via postsynaptic mGluR activation at a calyx synapse.
Kushmerick C, Price G, Tashenberger H, Puente N, Renden R, Wadiche JI, Duvosin RM, Grandes P & von Gersdorff H (2004). J. Neurosci., 24:5955-65.
A transgenic marker for newly born granule cells in dentate gyrus.
Overstreet LS, Hentges ST, Bumaschny V, de Souza FJ, Smart JL, Santangelo AM, Low MJ, Westbrook GL & Rubinstein M (2004). J. Neurosci. 24:3251-3259.
GABA release from proopiomelanocortin neurons.
Hentges ST, Nishiyama M, Overstreet LS, Stenzel-Poore M, Williams JT & Low MJ (2004). J. Neurosci. 24:1578-83.
Synapse density regulates independence at unitary inhibitory synapses.
Overstreet LS & Westbrook GL (2003). J. Neurosci., 23:2618-26.
Multivesicular release at climbing fiber-Purkinje cell synapses.
Wadiche, JI & Jahr, CE (2001). Neuron, 32:301-13.
Paradoxical reduction of synaptic inhibition by vigabatrin.
Overstreet LS & Westbrook GL (2001). J. Neurophys. 86:596-603.
Slow desensitization regulates the availability of synaptic GABAA receptors.
Overstreet LS, Jones MV & Westbrook GL (2000). J. Neurosci. 20:7914-7921.
Glutamate transporters contribute to the time course of synaptic transmission in cerebellar granule cells.
Overstreet LS, Kinney GA, Liu Y-B, Billups D & Slater NT (1999). J. Neurosci. 19:9663-9673.
Macroscopic and microscopic properties of a cloned glutamate transporter/chloride channel.
Wadiche, JI & Kavanaugh, MP (1998). J. Neurosci., 18:7650-7661.
Prolonged physiological entrapment of glutamate in the synaptic cleft of cerebellar unipolar brush cells.
Kinney GA, Overstreet LS & Slater NT (1997). J. Neurophys, 78:1320-1333.
A role for adenosine A2 receptors in the induction of long-term potentiation in the CA1 region of rat hippocampus.
Kessey K, Trommer BL, Overstreet LS, Ji T & Mogul D (1997). Brain Res., 756:184-190.
Metabotropic glutamate receptor mediated long-term depression in developing hippocampus.
Overstreet LS, Trommer BL, Colley PA, Slater NT & Pasternak JF (1997). Neuropharmacology, 36:831-844.
Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor.
Pekhletski R, Gerlai R, Overstreet LS, Huang X, Agopyan N, Slater NT, Abramow-Newerly W, Roder JC & Hampson DR (1996). J. Neurosci., 16:6364-6373.
Ion fluxes associated with excitatory amino acid transport.
Wadiche JI, Amara SG & Kavanaugh MP (1995). Neuron, 15:721-728.
Kinetics of a human glutamate transporter.
Wadiche JI, Arriza JL, Amara SG & Kavanaugh MP (1995). Neuron, 14:1019-1027.
AP5 blocks LTP in developing rat dentate gyrus and unmasks LTD.
Trommer BL, Kennelly JJ, Colley PA, Overstreet LS, Slater NT & Pasternak JF (1995). Exp. Neurol., 131:83-92.
Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex.
Arriza JL, Fairman WP, Wadiche JI, Murdoch GH, Kavanaugh MP & Amara SG (1994). J. Neurosci., 14:5559-5569.
Molecular cloning, functional expression and distribution of a rat neuronal nicotinic channel highly permeant to calcium.
Seguela P, Wadiche J, Dinelly-Miller K, Dani J & Patrick J (1993). J. Neurosci., 13:596-604.

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